Posted in

Cannabinoid Hyperemesis Syndrome: A Case Report and Review of Pathophysiology

In these cases, addiction treatment programs can provide the necessary support for successful recovery. While more people are becoming aware of the condition, there are several factors that can delay diagnosis and treatment. For one thing, it is often misdiagnosed as other conditions, delaying treatment and recommendations for cannabis abstinence. This can be a costly process, with one study suggesting costs as high $95,000 in 2012 to go through all the medical visits and testing that happened prior to the diagnosis. One study found a median time of 8 years from symptoms beginning to diagnosis – with some patients going up to 21 years with symptoms before a CHS diagnosis. Patients in that study went to the ER an average of 22 times for their symptoms before getting a diagnosis.

Addiction Treatment

We understand the complexities of addiction and work closely with individuals to create personalized recovery plans that address both the physical and psychological aspects of addiction. The exact cause Halfway house of Cannabinoid Hyperemesis Syndrome remains unclear, but there are several theories as to why it occurs in some chronic marijuana users. It is believed that prolonged marijuana use leads to overstimulation of the body’s endocannabinoid system, which is involved in regulating functions like mood, appetite, and gastrointestinal processes. What’s unlikely is that CHS is attributable entirely to pesticide contamination, as some cannabis advocates have suggested.

cannabinoid hyperemesis syndrome death

All-Time High: Majority Of Republicans Support Pot Legalization For First Time

cannabinoid hyperemesis syndrome death

These factors, which cause symptoms similar to those of CHS, may act as distractors in the development of a differential diagnosis, because they may cause symptom prolongation and overlap. For example, the prodromal phase described by Allen and others2 may be misinterpreted how long does it take to recover from cannabinoid hyperemesis syndrome in the presence of any of these factors. If that were not sufficiently ominous, observed mutations on the ATP-binding cassette transporter (ABCA1) could increase risks of future abnormal protein deposition in the brain, dementia, coronary artery disease and Type II diabetes (Feher et al., 2018). Thus, early diagnosis with appropriate genetic and health counseling are high priorities upon diagnosis.

‘Basically, they smoked weed’

cannabinoid hyperemesis syndrome death

Overlapping symptoms such as abdominal pain and cyclic vomiting are especially difficult to pinpoint to a specific illness. Studies eligible for inclusion included peer-reviewed articles, randomized controlled trials, observational studies, case reports, clinical trials, and systematic reviews focusing on CHS or comparing it with similar disorders like cyclic vomiting syndrome (CVS). Studies exploring novel treatments, diagnostic criteria, or the pathophysiology of CHS were also prioritized. To assess the burden of disease, Meltzer and his colleagues conducted a survey of 1,052 people who report suffering from cannabinoid hyperemesis syndrome. The researchers asked questions about frequency of use, duration of the habit, the age they started using the drug, and need for emergency department or hospital care. Cannabinoid Hyperemesis Syndrome is a condition that affects individuals who use marijuana regularly, particularly those who have been using it for years or in large quantities.

Patients

  • After applying these criteria, a selection of relevant studies was included in this narrative review.
  • By 2016, she thought she was dying, that she “must have some sort of cancer or something they can’t detect,” Queen said.
  • Although the exact cause of CHS is still being studied, experts believe the syndrome may be linked to how THC, the psychoactive component in cannabis, interacts with the brain and gut.
  • Although this study had some limitations, including self reported use of cannabis, Meltzer says it suggests a substantial risk of this painful and costly condition, especially for users who begin daily use of cannabis as adolescents.
  • When a patient presents with nonspecific symptoms, efforts must be increased to decrease the possibility of cognitive errors.

Once a person develops the condition, he or she has likely done something permanent. Persuading patients to accept this, however, can be difficult, Habboushe said. On the other side of the country, Dr. Jeff Lapoint and his colleagues saw an influx of patients with CHS symptoms about six years ago. Lapoint is the director of the division of medical toxicology at Kaiser Permanente Southern California and practices in San Diego, which he said is home to both craft beer and craft marijuana. Tetrahydrocannabinolic acid (THCA) is anti-emetic in laboratory animals (Rock et al., 2020), but is an https://pbtechconsultants.com/?p=14674 unstable molecule that decarboxylates to THC, and is likely problematic.

Leave a Reply

Your email address will not be published. Required fields are marked *